| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bf4d94c023cf905e02995d69e0c7385 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-14122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-14133
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70514
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
| filingDate |
2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c062b37f2331c0187c26030d8cad0be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3163516e15970dea6ab947f188ee9cfe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98cb556072cefba0badc0910c7dd41b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96b06946359bb506bba3ff975f7c6963 |
| publicationDate |
2016-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20160010618-A |
| titleOfInvention |
Polypeptides comprising a modified bacteriophage g3p amino acid sequence with reduced immunogenicity |
| abstract |
The present invention relates to a part of a filamentous bacteriophage gene 3 protein (g3p) which is bound to and / or capable of degrading amyloid, for example the N1-N2 part of g3p and its mutant and fragment Wherein the g3p amino acid sequence is modified via amino acid substitution so that when used in vivo, it is substantially less immunogenic than the corresponding wild-type g3p amino acid sequence. The polypeptides of the present invention retain their ability to bind and / or degrade amyloid. Moreover, the present invention relates to the use of these variants g3p-polypeptides in the treatment and / or prevention of diseases associated with misfolding or aggregation of amyloid. |
| priorityDate |
2013-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |