http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160008003-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17c6c7da627b7bead7208250127b52c2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2014-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8adf88ea2386d7d08d6e537c005da88a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cbe34805e4c8d913aaa7f2f501931e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0097e7fc787e104b00fab333302fc30 |
| publicationDate | 2016-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20160008003-A |
| titleOfInvention | Novel Cell Line for Evaluating Reactive Oxygen Species Level Induced Mitochondria, Composition Comprising the Same, and Uses Thereof |
| abstract | TECHNICAL FIELD The present invention relates to a novel cell line for measuring the amount of reactive oxygen species derived from mitochondria, a composition comprising the same, and uses thereof. More particularly, the present invention provides a cell line transformed with a first recombinant viral vector and a second recombinant viral vector described below: the first recombinant vector comprises a Reactive oxygen species modulator 1 (ROMO1) promoter; And a reporter gene-coding nucleotide sequence operatively linked to the sequence; The second recombinant vector may be a CMV (Cytomegalovirus) promoter; And a reporter gene-coding nucleotide sequence operatively linked to the sequence. The present invention also provides a composition for measuring the amount of reactive oxygen species expression, a composition for screening toxic substances, a method for producing the cell line, and a method for screening for a hepatotoxicity inducing substance. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101975366-B1 |
| priorityDate | 2014-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.