http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160005282-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17c6c7da627b7bead7208250127b52c2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B81B1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0619 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B81B1-00 |
filingDate | 2014-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b72d7781eb77d3ace5298728a9ec6102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12d08408ff7fdf083dce23f0dbf8c01b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4363e0461049b5e8244c79911f2a4e0 |
publicationDate | 2016-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20160005282-A |
titleOfInvention | Microfluidic chip and a method for preparing artificial neuronal network thereon |
abstract | The present invention relates to a microfluidic platform for the growth of unidirectional axons and to a method for culturing in vitro neurons comprising the same. More particularly, the present invention relates to a microfluidic platform capable of forming a unidirectional artificial neural network similar to an actual brain neural network by designing asymmetric microchannels using the growth characteristics of axons, and an in vitro neuron culturing method using the microfluidic platform . Using a microfluidic cell culture platform according to the invention in vitro (In By cultivating neurons in vitro , they can regulate the growth direction of axons and overcome the existing limitations and connect neuronal cells with two or more unidirectional neurons to form neural networks that simulate actual in vivo neuronal structures have. In addition, the microfluidic platform according to the present invention can be used as a brain or brain damage model because it can produce a neural network having a directional characteristic without any additional chemical coating or additional device using the growth characteristics of the neural axon. It can also be used for drug screening. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114968602-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114968602-B |
priorityDate | 2014-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID57449 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419557733 |
Total number of triples: 21.