http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150134443-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff283c7d6797987f01db547f606e6b32 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 |
| filingDate | 2014-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_181b8d2525a36caaa92b5dd73b83cff0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e92d6283552cf4175429df58379aed9b |
| publicationDate | 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20150134443-A |
| titleOfInvention | A lipophilic drug-loaded solid lipid nanoparticle surface-modified with N-trimethyl chitosan |
| abstract | The present invention relates to a process for preparing curcumin-loaded solid lipid nanoparticles coated with N-trimethyl chitosan; A curcumin-loaded solid lipid nanoparticle, wherein the solid lipid nanoparticle comprises palmitic acid, cholesterol and TPGS, wherein the solid lipid nanoparticle surface is coated with N-trimethyl chitosan, Loaded solid lipid nanoparticles; And The present invention relates to a curcumin preparation for oral administration comprising curcumin-loaded solid lipid nanoparticles as an active ingredient. The solid lipid nanoparticles loaded with curcumin coated with N-trimethylol chitosan of the present invention are stable in an acidic gastric environment due to the above coating, so that they can continuously release curcumin in the intestinal tract even when administered orally, . The solid lipid nanoparticles loaded with the curcumin coated with N-trimethylchitosan can transmit drug to the brain tissue through the blood-brain barrier to treat cancer diseases as well as brain diseases such as Alzheimer's disease and brain glioma. Or a pharmaceutically acceptable salt thereof. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115120563-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220092106-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110051654-A |
| priorityDate | 2014-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.