| abstract |
The present invention relates to microRNA-127 as a diagnostic marker for muscle aging, and more specifically, the present invention relates to a composition for diagnosing muscle aging comprising an agent for measuring the expression level of miRNA-127 or a fragment thereof, Diagnostic kit, and miRNA-127 or fragment thereof for the diagnosis of muscle aging. Various miRNAs, including miRNA-127, provided by the present invention have not only a decrease in muscle atrophy and accompanying muscle weakness due to aging, but also a decrease in energy metabolism resulting from aging, which can accompany diseases such as obesity and diabetes. It can be widely used as a marker having excellent effect in development of a muscle aging diagnostic kit and searching for substances inhibiting muscle aging because it can be used as a marker for diagnosing the progress or invention and the degree of aging. |