| abstract |
Claims 1. A compound of formula (I), or a stereoisomer, enantiomer or tautomer thereof, or a mixture thereof; Or a pharmaceutically acceptable salt or solvate thereof, is described herein. Such compounds have activity as SHIPl modulators and can therefore be used to treat any of a variety of diseases, disorders or conditions that can benefit from SHIPl modulation. Also disclosed are compositions comprising a compound of formula I in combination with a pharmaceutically acceptable carrier or diluent, and methods of modulating SHIP1 by administering such compounds to an animal in need of modulation of SHIP1 are also disclosed. (I) Wherein R 1 , R 2 , R 3 , R 4a , R 4b , R 5 , R 6 and R 7 are defined herein. |