abstract |
The compounds of formula I wherein L 1 , L 2 , L 3 , L 4 , R 1 , R 4 , R 5 , R 6 and s are as defined herein are disclosed herein. The compounds of formula I are EP 4 agonists useful in the treatment of glaucoma, osteoporosis, fracture, periodontal bone loss, orthopedic implantation, hair loss, neuropathic pain and related disorders. Pharmaceutical compositions and methods of treating conditions or disorders are also described. (I) |