http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150112439-A

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filingDate 2014-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26fed7a850637d17fb6784df70fa5f24
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publicationDate 2015-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20150112439-A
titleOfInvention Pharmaceutical composition for prophylaxis and treatment of acne, skin external preparation, and method for producing extract of physostegia virginiana
abstract The present invention relates to a method for drying a flower bug, A powdering step of pulverizing the tail of the dried flower bug to produce a powder; A solvent extraction step of extracting a tail of the powdered flower bug into an extraction solvent to obtain an extract; A filtration step of filtering the extract with a filter paper to remove precipitates and obtaining an extract filtrate; Evaporating and concentrating the extracted filtrate by evaporation and decompressing in an evaporator; And a freeze-drying step of freezing and concentrating the concentrated and concentrated evaporated liquid in a freeze-dryer to remove moisture to obtain a dried extract. The method of extracting a tail bug's tail extract and the tail extract of the bug bug extracted from the bug include 0.001 to 35 wt% As an active ingredient and having an excellent antimicrobial activity against Propionibacterium acnes. The present invention also provides a pharmaceutical composition for preventing and treating acne, which has excellent antimicrobial activity against Propionibacterium acnes. According to the present invention, it is possible to easily obtain a tail bug extract of a bug bug, to contain a tail bug extract of a natural bug bug as an active ingredient, to be safe and free from rejection and side effects even if it is used for a long time, It has an excellent antimicrobial action against Onyptia bacterium acnes, and is effective in preventing and treating acne by suppressing or alleviating inflammation.
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