abstract |
The present invention relates to a method for producing a liposome comprising lyophilization of polyethylene glycol and spacer groups which are hydrophilic and liposynthesis, oligopeptides including lysine, cations in which one species selected from the group consisting of aminoethanol, aminopropanol, aminobutanol, aminopentanol and aminohexanol is introduced The present invention relates to a polyphosphazene-drug conjugate compound chemically bound to a hydrophobic drug and a method for preparing the same, and the compound of the present invention is excellent in cancer tissue selectivity and low in toxicity, It is a new material with a high possibility of practical use. |