abstract |
The present invention relates to a prodrug suitable to be effectively used for oral delivery of darbagtran, which is useful for the treatment or prevention of stroke and systemic embolism, comprising a compound represented by the formula (1), a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof . ≪ Formula 1 > The compound represented by the formula (1), a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof is useful for the treatment or prevention of stroke and systemic embolism, and the absorption rate of dabigatran, that is, bioavailability is improved, Suitable for use. |