http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150100152-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5351c62aee4203f2be2944f21a6def2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B10-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00 |
| filingDate | 2014-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da749db29736b50a2dceec52563fc89a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62ca2707e2518e785d8bfe90aca3ad65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_408864b7da7139944ab544e4024d721d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb20cfc1888bbc264c848009b4e2a286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a807cda354d54cb58fb77ca69330dad |
| publicationDate | 2015-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20150100152-A |
| titleOfInvention | Method for hepatotoxicity prediction using in silico technology |
| abstract | The present invention relates to a method for predicting hepatotoxicity using a silico technique. The method for predicting hepatotoxicity using the in silico technique of the present invention includes a step of collecting information on hepatotoxic compounds from the US Food and Drug Administration (FDA) database (Human Liver Adverse Effect Database), designating the hepatotoxic compound as a chemical structure defined by a fingerprint presenter A step of calculating a distribution of information Gain (IG), which is the importance of a fingerprint presenter in the calculated prediction model, a step of calculating a stabilized IG optimum value and a fingerprint presenter having a high importance in the distribution diagram And using the selected fingerprint presenter, a support vector machine-based machine learning method can achieve high toxicity prediction power of 78% to 95%. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190005398-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11705224-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180060968-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102285340-B1 |
| priorityDate | 2014-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.