abstract |
The present invention relates to an anti-KRS antibody that selectively binds to KRS (Lysyl-tRNA synthetase) and uses thereof, and more specifically to an antibody or fragment thereof that binds to human KRS, a method for producing the antibody, and a cancer or autoimmune disease And compositions for the diagnosis of inflammatory diseases. Since the antibody or fragment thereof of the present invention specifically binds to human KRS and is not cross-reactive with other proteins including the same ARS family, it is possible to detect and inhibit KRS. Therefore, KRS detection and KRS-related diseases such as cancer or autoimmune diseases May be used for diagnostic purposes of inflammatory diseases. |