| abstract |
(Preferably clomipramine hydrochloride) as the first active ingredient and sildenafil or a pharmaceutically acceptable salt thereof (preferably, sildenafil Citrate), the present invention provides pharmaceutical preparations with improved stability of clomipramine and methods of preparing such pharmaceutical preparations. In particular, the present invention provides a pharmaceutical preparation comprising the above two active ingredients, wherein the pharmaceutical preparation is prepared using the wet granulation method, wherein the stability of the clomipramine is improved, and a method for producing such a pharmaceutical preparation. |