| abstract |
The present invention belongs to the field of chemical medicine and specifically relates to a compound having a heteroaryl group alkyne structure represented by the formula (I) or a pharmaceutically acceptable salt, isomer, N-oxide, solvate, Drugs, and pharmaceutical compositions containing such compounds, and the use of such compounds or compositions in the manufacture of medicaments. The compounds of the present invention have a relatively strong inhibitory effect on BCR-ABL kinase, and can be used for tumor diseases and the like. |