| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5351c62aee4203f2be2944f21a6def2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-65 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2013-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_778d89bdc869420adcf2e4eb39bb7c09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1928ece577c533f0e0c508255dfdb001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_add97adcd26d40a379665a5f539d37e3 |
| publicationDate |
2015-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20150069375-A |
| titleOfInvention |
A Composition for Promoting Chondrogenesis from Stem Cells |
| abstract |
The present invention relates to a stem cell, more specifically, a composition for promoting differentiation of mesenchymal stem cells into chondrocytes, a composition for preventing or treating cartilage damage disease, and a screening method for the same. The present invention newly identified miR-495 as an miRNA that inhibits the differentiation of stem cells into chondrocytes, and confirmed that it is possible to efficiently differentiate pluripotent stem cells into cartilage cells through inhibition thereof. The present invention can be usefully used for the fundamental prevention and treatment of cartilage damage-related diseases including degenerative arthritis through regeneration of lost cartilage tissue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019231299-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019078587-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190043413-A |
| priorityDate |
2013-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |