| abstract |
An antitumor agent having excellent antitumor effect and safety, comprising an anti-tumor compound represented by the following formula and an antibody represented by the following formula: -L 1 -L 2 -L P -NH- (CH 2 ) n 1 -L a -L b c -L-antibody, characterized in that combined via a linker having the structure shown by-drug conjugate (antibody binding in the ends of the L 1, and the anti-tumor compound is a binding site to the nitrogen atom of the amino group in position 1 , At the end of L c ). |