| abstract |
The present invention relates to a method for the determination of the level of biomarkers that are IL6 and / or IL8 present in a biological sample obtained from an object, such as 2,2-dimethyl-N- ((S) -6-oxo-6,7-dihydro Dibenzo [b, d] azepin-7-yl) -N'- (2,2,3,3,3-pentafluoro-propyl) -malonamide And to a method of measuring the same. The present invention also provides a method of treating a patient suffering from a proliferative disorder comprising administering to a patient suffering from a proliferative disorder a therapeutically effective amount of 2,2-dimethyl-N - ((S) -6-oxo-6,7- 7-yl) -N'- (2,2,3,3,3-pentafluoro-propyl) -malonamide and an anti-IL6 and / or anti-IL8 agent . |