abstract |
The present invention provides a process for preparing a compound of formula XI or XII, wherein R < 1 > is hydrogen, by reacting a compound of formula XIII < EMI ID = 15.1 > with a compound of formula XIV or XV in the presence of a transition metal catalyst, a ligand suitable for use with said catalyst, to provide. The present invention also provides novel intermediates. (XI) (XII) ≪ Formula (XIII) <Formula XIV> (XV) Wherein X, Y, Z, A, B and E are as defined herein. |