| abstract |
An embodiment of the present invention provides a method of treating a subject suffering from a disease or condition that is characterized by the following three levels of beta cell physiology: (i) glucose metabolism, (ii) membrane receptor function, and (iii) transcription resulting in in vivo formation of beta cells in the pancreas Stimulates the factor. In certain aspects, the methods include the integration of three levels of cellular physiology: metabolism, membrane receptor function, and gene transcription. Multilevel integration of cellular physiology produces a synergistic effect on beta cell formation. |