| abstract |
Which are useful as integrin receptor antagonists mediating pathological processes of angiogenesis and fibrosis, and methods of treating symptoms mediated by these integrins by inhibiting or antagonizing integrins and novel pharmaceutical agents useful in pharmaceutical compositions Lt; / RTI > The novel pharmaceutical materials include those of the following formulas: (I) The substituent groups in the formula are as defined in the specification. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical materials. Methods and intermediates useful for making pharmaceutical materials, and methods of using pharmaceutical materials are also provided. |