| abstract |
It is an object of the present invention to provide a novel protein material useful for the prevention and treatment of various bone diseases such as osteoporosis, fracture, rheumatism and arthritis by being safely and routinely ingested. It is also an object of the present invention to provide a bone-strengthening food or feed useful for prevention or treatment of various bone diseases such as osteoporosis, fracture, rheumatism and arthritis by oral ingestion. The above object is achieved by a pharmaceutical composition containing 2 to 15 mg / 100 mg of angiogenin and / or angiogenin hydrolyzate, and further comprising a lactoperoxidase and / or lactoperoxidase degradation product in combination with angiogenin and / And the protein material contained in the range of 0.3 to 20 mass ratio with respect to the geninolytic substance. By ingesting these protein materials, it is possible to prevent and treat various bone diseases such as osteoporosis, fracture, rheumatism and arthritis, in particular, strengthening bones. |