| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a43ef275ae6f6fafc66975041eb60aa7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-06013 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y108-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-06013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 |
| filingDate |
2013-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38d556013bd7dfc1598b7b3cdb8d26df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_280545c082c24724c04947c4b9131262 |
| publicationDate |
2015-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20150030242-A |
| titleOfInvention |
Cells for producing recombinant iduronate-2-sulfatase |
| abstract |
The present invention provides, among others, methods and compositions for the production of recombinant I2S proteins with improved efficacy and activity using cells to co-express I2S and FGE proteins. In some embodiments, the cells according to the invention are engineered to over-express recombinant I2S and FGE proteins simultaneously. The cells according to the present invention are adaptable to various cell culture conditions. In some embodiments, the cells of the invention are adaptable to large-scale suspension serum-free media. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200090935-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11498949-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150063018-A |
| priorityDate |
2012-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |