http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150028231-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b416a8c0d2b0f1c3d6026d932027af |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61 |
filingDate | 2013-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6b6d3413267e78f53b13002b178d3ad |
publicationDate | 2015-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20150028231-A |
titleOfInvention | Methods for reducing levels of protein-contaminant complexes and aggregates in protein preparations by treatment with electropositive organic additives |
abstract | (E. G., Ethylene oxide, e. G., ≪ / RTI > in combination with a low concentration of a positive charge organic additive, e. G., Urea, uric acid or allantoin) or an organic modulating agent (e. G., A nonionic organic polymer, surfactant, organic solvent or ureide) A method is provided for reducing aggregate levels in antibodies and other protein preparations by treatment with a pharmaceutically acceptable carrier, e. G., Cadidine, chlorhexidine or polyethyleneimine. Some aspects of the invention are associated with methods of reducing aggregate levels in combination with purification of cell culture harvest. It also involves combining these capabilities with other purification methods to achieve the desired level of final purification. |
priorityDate | 2012-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 216.