| titleOfInvention |
Compounds with (1e,6e)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof |
| abstract |
The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl) -propenal moiety. The compounds and compositions of the present invention are useful for the treatment and prevention of medical conditions including androgen-related symptoms, androgen-related inflammation, wound healing (the compound aids wound healing), acne, rheumatoid arthritis, psoriasis, injection and alopecia; Kennedy ' s disease (spinal cord and soft muscular dystrophy or SBMA), polyglutamine-mediated motor neuron degeneration, prostate cancer, bladder cancer, breast cancer, ovarian cancer, hepatocellular carcinoma and pancreatic cancer; And other medical conditions described herein. Treatment of such a medical condition includes administration of a therapeutically effective amount of any of the disclosed compounds, derivatives or pharmaceutical compositions thereof, to individuals suffering from the medical conditions described herein. |