http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150011386-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0bc300b100406f6519b33d2e76088fc1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-547 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 |
| filingDate | 2012-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4b0b4256207665a04f6e116fac4e4fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7627ecf1695a88fd23ef2c07ef2c2e7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e474d93c94fd2f02ac5ec74b02c6eab4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_198335de842d89c652b2bbd1a9da3790 |
| publicationDate | 2015-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20150011386-A |
| titleOfInvention | Complex compounds of germanium, methods for producing same, and drugs |
| abstract | The present invention relates to the development of drugs intended for the prevention and / or treatment of viral diseases, in particular viral diseases caused by herpes viruses. A complex compound of germanium having the general structural formula Ge x [AD] [CA] y [AA] z (I): wherein AD is a derivative of a purine-based nitrogen base having antiviral activity and is selected from acyclovir, valacyclo Guanine derivatives such as birr, gancyclovir and penicyclovir, or adenine derivatives such as vidarabine; CA is a hydroxycarboxylic acid which may be selected from (but not limited to) an acid such as citric acid, lactic acid and malic acid; AA is an amino acid that can be selected from a variety of? -Amino acids such as arginine, glycine, lysine and threonine, wherein x = 1-2, y = 2-4, and z = 0-2. Compounds are proposed. Complex compounds of germanium have high levels of antiviral and immunostimulatory activity and can readily dissolve in water. The abovementioned compounds can be prepared by a process comprising the steps of preparing an aqueous suspension of germanium dioxide, a hydroxycarboxylic acid, a derivative of a nitrogen base of the purine series and optionally, but preferably, adding an amino acid, Heating at a temperature of 40-100 DEG C for 3-14 hours, and removing water from the solution to produce a complex compound of germanium. |
| priorityDate | 2012-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.