Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17c6c7da627b7bead7208250127b52c2 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate |
2014-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1a7e448d7c6113c8eb2507355a79475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_782aa9850a6c16e6b8e85d624242441e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b4ae4709906d66391f77bbb3a0b6eb2 |
publicationDate |
2015-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20150009448-A |
titleOfInvention |
Development of a novel emphysema-related animal model using insulin-like growth factor 2 (IGF2) |
abstract |
The present invention relates to a method of producing an emphysema-induced animal model, and more particularly to a method of producing an emphysematous animal model, comprising over-expressing insulin-like growth factor 2 (IGF2) will be. The transgenic animal produced by the method of the present invention is capable of confirming pulmonary lesions caused by IGF2 locally expressed only in pulmonary epithelial cells in lung tissues unlike the conventional model, As a new molecular marker for the treatment and prevention of emphysema, it can be used as an effective model mouse for screening for emphysema therapeutics. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200088559-A |
priorityDate |
2013-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |