http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150008556-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67c4447c82594efcbbd319e64f6bd80b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-10 |
| filingDate | 2013-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c3e2c847a4204fcc7346581c5a18df9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5b9e7c3398156e332106892b1c28132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f81e1300a8917d78e45cd95d95226e5 |
| publicationDate | 2015-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20150008556-A |
| titleOfInvention | Producing method of biomaterial for tissue regeneration |
| abstract | The present invention relates to a method for producing a biomaterial for tissue regeneration having remarkably improved qualities. The produced biomaterial for tissue regeneration includes sodium hyaluronic acid as a main ingredient. The stability and durability of a product are improved through a plurality of cross-linking reactions. Components that are harmful to the human body are completely removed by performing a plurality of precipitating, re-hydrating, washing, and sterilizing/disinfecting steps. The method comprises: a first step of producing a sodium hydroxide solution; a second step of mixing and agitating the produced sodium hydroxide solution with a particular quantity of sodium hyaluronic acid; a third step of adding and agitating a BDDE cross-linking agent in a mixed solution produced through the second step; a fourth step of cross-linking a sodium hyaluronic acid gel raw ingredient generated through the third step; a fifth step of adding and precipitating ethanol in the sodium hyaluronic acid gel raw ingredient cross-linked through the fourth step, removing ethanol, and re-hydrating precipitated hyaluronic acid gel by adding a PBS solution; a sixth step of washing the sodium hyaluronic acid gel raw ingredient precipitated and re-hydrated through the fifth step by a particular washing PBS solution; a seventh step of mixing the sodium hyaluronic acid gel raw ingredient washed through the sixth step with a particular PBS solution at a particular ratio to pulverize the same and remove bubbles; an eighth step of filling a prefilled syringe with a biomaterial for sodium hyaluronic acid gel tissue regeneration produced through the seventh step; and a ninth step of performing a high pressure sterilizing and disinfecting procedure on the prefilled syringe filled with the sodium hyaluronic acid gel tissue regeneration produced from the eighth step. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210082077-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200127986-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200070125-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200128383-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017131298-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110016152-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180052261-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200128382-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108602898-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020116999-A1 |
| priorityDate | 2013-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.