abstract |
The present invention relates to a process for the preparation of 6-bromo-a- [2- (dimethylamino) ethyl] -2-methoxy- alpha-1-naphthalenyl- 2, 1 ', 2'-f] [1,3,2] dioxaphosphepin 4-oxide or derivatives thereof, especially (11bR) -4-hydroxydinaphtho [ 1-d: 1 ', 2'-f] [1,3,2] dioxaphosphepin 4-oxide as a resolving agent to obtain (αS, βR) -6- Ethyl] -2-methoxy -? - 1-naphthalenyl -? - phenyl-3-quinoline ethanol. |