| abstract |
The present invention relates to a granule comprising tadalafil or a pharmaceutically acceptable salt thereof as an active ingredient; Granules of specific particle size and density produced by wet processing; At least one disintegrant selected from the group consisting of sodium starch glycolate, carboxymethylcellulose calcium, starch, alginic acid, and sodium alginate; And a pharmaceutically acceptable additive. The tablet of the present invention has excellent dissolving rate of tadalafil, has a small foreign substance feeling in the oral cavity, has no discomfort even when disintegrated in the oral cavity with improved taste and flavor, can be chewed without water, The PDE-5 inhibitor can be used for the treatment of erectile dysfunction and pulmonary hypertension patients. |