abstract |
It is an object of the present invention to provide a capsule formulation comprising a phosphonoxymethyl derivative of rabuconazole, which inhibits the dissolution delay due to storage regardless of the amount of the phosphonoxymethyl derivative of rabuconazole. The present invention relates to a process for the preparation of {[( 1R , 2R ) -2- [4- (4-cyanophenyl) -1,3-thiazol- -1- (1 H -1,2,4-triazol-1-ylmethyl) propyl] oxy} methyl dihydrogenphosphate or a pharmacologically acceptable salt thereof, or a solvate of any of An encapsulating material, and a capsule shell that does not contain gelatin. |