| abstract |
The present invention relates to a composition for detecting copper ions having an extremely high sensitivity and a high selectivity, a fluorescent chemical sensor including the same, a method of producing the same, a selective detection method of copper ion, a screening method of a copper ion chelating agent and a chelating effect of a copper ion chelating agent ≪ / RTI > The present invention can be applied to the detection of copper ions in biological samples such as rivers, lakes, oceans and the like, as well as biological samples such as plasma, serum and urine. The present invention can be used for evaluating the efficacy of existing copper ion chelating agents and for developing new copper ion chelating agents It is also applicable to high throughput screening. In addition, it is possible to qualitatively and quantitatively detect copper ions in intracellular and in vivo serum, and it can be applied as a diagnostic kit for diseases. |