abstract |
The present invention provides peptides that bind to a tissue factor pathway inhibitor (TFPI), including TFPI-inhibiting peptides, and compositions thereof. Peptide complexes are also provided. The peptide inhibits TFPI, enhances thrombin formation in the coagulation factor-deficient individual, increases thrombus formation in the subject, treats blood coagulation disorders in the subject, purifies TFPI, and identifies TFPI-binding compounds Lt; / RTI > |