abstract |
The present invention relates to a composition for improving wrinkles containing garlic-derived uracil as an active ingredient, which comprises caffeic acid (CA), s-allylcysteine (SAC) and uracil uracil) inhibited the MMP enzyme through regulation of the NF-κB signal, confirming that UVB-induced wrinkles were effectively improved. This suggested the possibility that CA, SAC and uracil, active substances isolated from garlic, could be used as anti-skin aging agents in UVB-induced photoaging. |