http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140137871-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fd15d8ebb22202b5cfe2b109cd922c5 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
| filingDate | 2013-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abcfcfcee67e553957c56629fbf5a7ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b076ee2e173ea9dbf76859f679c6e1d |
| publicationDate | 2014-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20140137871-A |
| titleOfInvention | Single nucleotide polymophism of Human multidrug and toxin extrusion 2 gene and use thereof |
| abstract | The present invention relates to a single nucleotide polymorphism (SNP) in a human multidrug and toxin extrusion 2 (MATE2-K) gene and its use. It is intended to identify mutations occurring in the MATE2-K gene, A plasmid having a haplotype was prepared and when the promoter region had g-130G> A, g.-609G> A and g.-396G> A mutations, the activity of the promoter was significantly Respectively. In addition, by confirming that the excretion of metformin was increased when the mutation occurred in 45 subjects, the MATE2-K single nucleotide polymorphism (g.-130G> A; rs12943590, g.-609G> A ; rs758427 and g.-396G >A; rs34834489) can be usefully used as a kit for confirming the reactivity of a drug transported by MATE2-K and a confirmation method using the same. |
| priorityDate | 2013-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 517.