http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140136250-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae372ddaa494f2face39592b0429cc16 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate | 2013-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb10f3203549306eb13cb9c609ef1a89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5d16d6b81d31825b7a3b7805fe24f52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62e427270f0591b2b36fd84914a7c365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_350dcf6e6919e1f39acf7b4a5ccda903 |
| publicationDate | 2014-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20140136250-A |
| titleOfInvention | Methods for zebrafish -Based Screenig Diabetes Therapeutics |
| abstract | The present invention relates to a zebrafish-based screening method of a diabetes therapeutic agent and a pharmaceutical composition for preventing or treating diabetes. According to the present invention, a zebrafish-based screening system combining a fluorescent glucose-inducing factor, which is a fluorescent-tagged glucose analogue, with the experimental utility of an animal model of a zebrafish, is established to produce a candidate antidiabetic agent candidate There is an effect that detection can be performed quickly and conveniently. In addition, it is possible to conveniently and rapidly measure the amount of glucose-induced factor intake by measuring the amount of fluorescent glucose-derived factor that is ingested in the zebrafish, and the necessity of an ancillary facility and radioactive purification treatment due to the use of conventional radioactive glucose tracer There is an advantage to remove. In addition, the zebrafish-based system is capable of performing the accompanying toxicity analysis, being simple in housing, capable of ingesting glucose upon contact with zebrafish and fluorescent glucose inducer, thus eliminating the need for advanced techniques such as microinjection, There is an advantage in that input cost and time can be reduced in performing large-scale based screening. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019027326-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-2019390-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109220911-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109220911-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10379108-B2 |
| priorityDate | 2013-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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