| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d77e120d1588e76c73afc1a3197a126 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3084
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 |
| filingDate |
2013-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e24c2328233a17be099b1aff74a8b29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a116544520c2b9b5abb997d6b62d7cf8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34d5b57856f919bcd63780efb95a35a1 |
| publicationDate |
2014-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20140126349-A |
| titleOfInvention |
Recombinant antibodies having dual specificity for gangliosides and use thereof |
| abstract |
The present invention relates to novel monoclonal antibodies and fragments of said antibodies, wherein said antibodies and fragments thereof exhibit bispecificity and high affinity for N-acetyl GM3 and N-glycolyl GM3, and other gangliosides are not recognized Do not. In another embodiment, the present invention relates to a method of treating tumors using the antibody and fragments of the antibody, wherein a significant expression of either of the two antigens recognized by the antibodies or a mixed expression of both antigens . Similarly, the present invention relates to the use of the antibodies in the diagnosis of tumors expressing at least one of the two variants of GM3 ganglioside. |
| priorityDate |
2012-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |