| abstract |
A pharmaceutical composition comprising a chemical substance or a chemical substance that inhibits ubiquitin activating enzyme (UAE); And a method of using a chemical, each of which is a compound of formula ( I ) or a pharmaceutically acceptable salt thereof: Wherein, Y is < RTI ID = 0.0 & gt ; ( II ) < W, Z, XY , RY1 , RY2, and RY3 are defined herein. These chemicals are useful for treating cell proliferative disorders including disorders, particularly cancer. |