| abstract |
The present invention relates to a composition for preventing hair loss and promoting hair growth, and more particularly to a composition for preventing hair loss and promoting hair growth, which comprises a copper tripeptide, a nicotinoyl tripeptide, an octapeptide, a pyrrolidinyl diaminopyrimidine oxide pyrrolidinyl diamino pyrimidine oxide, arginine, azelaic acid, pea extract and fruit juice extract of Bowl Palm as an active ingredient. The composition of the present invention promotes cell proliferation of dermal papilla cells and keratinocytes by activating Akt, which is a MAPK pathway, particularly a cell growth factor, Erk, and a cell survival factor, inhibits cell proliferation by inducing the pro-apoptotic factor Bax protein expression and Bcl-2 protein expression, which is an anti-apoptotic factor, as well as antioxidant activity. Showing growth promoting effect. Therefore, when the composition of the present invention is used as an external preparation for hair, a cosmetic preparation, a cleansing agent, etc., excellent hair loss prevention and hair growth promotion effect can be expected without side effects. |