abstract |
It is an object of the present invention to provide a compound having excellent Syk inhibitory activity and a pharmaceutical composition. According to the present invention, a nicotinamide derivative represented by the following general formula (I) or a salt thereof is provided. Wherein, R 1 is a group represented by the following formula (II-1), (III-1), or (IV-1) [Wherein R 3 , R 4 , R 5 , n and X 1 are as defined in the specification] R2 is pyridyl, indazolyl, phenyl, pyrazolopyridyl, benzisoxazolyl, pyrimidinyl, or quinolyl group which may have at least one substituent. |