| abstract |
In a first embodiment, the present invention provides a porous inorganic support material having a film of a cross-linked polyvinylamine comprising an amine group bonded to the surface of a porous inorganic solid support material through an electron donor / acceptor interaction with a derivatized amine group, To an adsorbent comprising a solid support material. In a second embodiment, the present invention is directed to an adsorbent comprising a solid support material having a surface comprising a moiety of the formula (I) wherein the moiety is selected from the group consisting of a bulk solid support material itself or a polymer Is attached to the functional group on the surface of the film through a covalent bond. The invention also relates to the use of an adsorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in the field of chromatographic applications. |