Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_745a75b0350f49480798ef5ab913bc0a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2013-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8818e1971eb67c3acaa5fee7aaf8b2a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8941bcc40ba66b9f81f53cdfcfbda2cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c1a4106ff0fdc22e2ce7143e5a780ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88c7b0f849c1c046ab389606c0ad45d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4446a8472199e183ef6f03461ad9452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0df635c5778c427307d3e8c399a8ecbc |
publicationDate |
2014-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20140097713-A |
titleOfInvention |
Biomarker composition for diagnosis of bortezomib resistance comprising mitochondrial calcium uniporter and diagnostic kit using the same |
abstract |
The present invention relates to a biomarker composition for bortezomib resistance diagnosis used as a therapeutic agent for multiple myeloma comprising an MCU (mitochondrial calcium uniporter), and a diagnostic kit using the same. And a bortezomib resistant diagnostic biomarker composition comprising the protein or a specific antibody thereof, wherein the bortezomib resistant diagnostic kit comprising the composition is provided. Also, the present invention provides a method for diagnosing bortezomib resistance, comprising measuring mRNA expression level of an MCU (mitochondrial calcium uniporter) gene or expression level of a protein encoded by the gene from a sample of multiple myeloma patients and comparing the expression level with a normal control sample do. |
priorityDate |
2013-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |