http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140091739-A

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filingDate 2012-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3379d23b0bf5a10d9ebdd6e70a067c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3286f640ab592dd14959e06292adab6
publicationDate 2014-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20140091739-A
titleOfInvention Process of purification of teicoplanin
abstract The present invention relates to a process for the purification of teicoplanin, in particular by adsorption of certain dissolved components from the filtrate of a fermentation broth of actinophrenes tecomycetix cultures on a commercially available hydrophobic or slightly polar adsorbent resin, The present invention relates to a method for efficiently removing impurities by selective elution of a product from a resin. According to the invention, the method comprises the step of contacting the water-miscible organic solvent in an aqueous solution in various purification step steps, for example in the above-mentioned elution step and / or in an ultrafiltration step on a 3-100 kDa cut- And the use of mixtures. The method further comprises treating the teicoplanin solution with charcoal, for example after elution and before ultrafiltration. Preferably, the water-miscible organic solvent is selected from the group consisting of C 1 -C 4 alcohols, C 3 -C 4 ketones or C 2 -C 4 nitriles.
priorityDate 2011-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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