| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cdff310342a50f662ea676068262e83b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-663
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate |
2011-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97c38294ea5bfe46cd69a4dc366b9499
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1308be2af4de4c6156cd2f639fb4d4c |
| publicationDate |
2014-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20140075638-A |
| titleOfInvention |
Stable effervescent bisphosphonate formulations with rapid solubilization characteristics |
| abstract |
The present invention is a stable, effervescent tablet, granule, or powder composition free of excipients capable of reacting with a foamable organic acid component, comprising an effective amount of a bisphosphonate bone resorption inhibitor; A foamable organic acid component; And a foamable base component; The composition does not contain a polyol binder and a refined lubricant; Having a dry loss of 0.25% (m / m) or less; Has a complete disintegration time of 180 seconds or less when placed in 3 to 8 ounces of water at 5 to 20 占 폚; And the bisphosphonate is incorporated as micronized particles or by spray drying and is completely dissolved in water within 2 minutes without stirring. |
| priorityDate |
2010-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |