| abstract |
The pyrazol-4-yl-heterocyclyl-carboxamide compound of formula (I), or a stereoisomer, geometric isomer, tautomer or pharmaceutically acceptable salt thereof, is useful for the inhibition of Pim kinase and for the inhibition of Pim kinase- ≪ / RTI > Disclosed are methods of using compounds of formula I for in vitro, in situ and in vivo diagnosis, prevention or treatment of such disorders or related pathological conditions in mammalian cells. (I) Wherein X is thiazolyl, pyrazinyl, pyridinyl or pyrimidinyl. |