http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140073464-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb8f3eba86915d967beefc175437273a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-04 |
| filingDate | 2012-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d46ba3b046f99f1264fbcb6c297f26c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06880aaeba9a219db892e3604ab58d3f |
| publicationDate | 2014-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20140073464-A |
| titleOfInvention | Hsp90 inhibitors |
| abstract | The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof: Formula 1 In Formula 1, In Formula 1, (a) each of Z 1 , Z 2 and Z 3 is independently CH or N; (b) Y is S; (c) Xa and Xb are O; (d) Xc is -CH 2 - and; (e) X 2 is -NR 1 R 2 , wherein R 1 and R 2 are each independently selected from the group consisting of H, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, Alkyl, heteroalkyl, heterocycloalkyl, aryl, heteroaryl, alkylaryl, arylalkyl, alkylheteroaryl, heteroarylalkyl, or alkylheteroarylalkyl; (f) X < 4 > is hydrogen or halogen; (g) R is R 10 -NH-R 11 , wherein R 10 is ethylene or propylene and R 11 is branched alkyl. The present invention also provides a composition comprising an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, and a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof in the same conditions as a cancer which overexpresses Her- To a patient in need thereof, comprising administering to a patient in need of such treatment or prevention a therapeutically effective amount of the Her-kinase. |
| priorityDate | 2011-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.