| abstract |
The present invention relates to a monobig extract having anti-inflammatory activity, and more particularly, to a composition for preventing or treating an inflammatory disease, which comprises a single-leaf extract as an active ingredient. The instant extract of the present invention can inhibit inflammation effectively because it has both nitric oxide (NO) production inhibition, inflammatory cytokine production inhibition, inflammatory chemokine production inhibition, prostaglandin E2 production inhibition and STAT1 phosphorylation inhibition But it is a safe substance in the body which does not cause toxicity to cells, and can be usefully used in the manufacture of medicines for treating inflammatory diseases and health functional foods. |