| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_700ff9a01db2075489cb7ed87392dc28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41a639aa11b9b2f8063a3e6b8b22b557 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06 |
| filingDate |
2012-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58cd66d852108656f508a3e0d2b1f4d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6846dca7bebfe668a467d0f7c85b4b07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cfa4f77bcdf16d5660a376220da8294
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3123391a6eb8bc231a8a96cd04795453
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f677f3749d3dd849d5eb80063e979c06 |
| publicationDate |
2014-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20140062088-A |
| titleOfInvention |
Methods for reducing the thrombolytic potential of plasma-derived immunoglobin compositions |
| abstract |
The present invention provides methods for reducing amidolytic and anti complement activity (ACA) content of immunoglobin compositions through the use of cation exchange chromatography. In certain embodiments, the present invention provides a method of collecting the leading edge of a cation exchange eluate to reduce XI factor and / or XIa factor and / or ACA content of the immunoglobin composition. The present invention also provides immunoglobin compositions with reduced levels of amidolytic activity, Factor XI and / or Factor XIa and / or ACA content. |
| priorityDate |
2011-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |