| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_951ade9cb9f29eb8a29ddae1e2fc87e3 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2012-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77cfe9d065eace63490053ea94fc7e13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62b952e07daf5afd445fff17cb64ea36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ebd3d6a8d182c0dbba78664df78f92a |
| publicationDate |
2014-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20140060134-A |
| titleOfInvention |
Composition for preventing or treating cancer comprising miR-186, miR-216b, miR-337-3p and miR-760 as an active ingredient |
| abstract |
The present invention relates to a composition for preventing and treating cancer comprising as an active ingredient a nucleic acid molecule consisting of miR-186, miR-216b, miR-337-3p and miR-760. The miR-186, miR-216b, miR-337-3p and miR-760 according to the present invention combine with each other in cancer cells to inhibit the expression of CKII alpha gene, thereby inducing the production of ROS and the expression of p53 and p21 Induces cell senescence in cancer cells and thus has an excellent effect of inhibiting the proliferation of cancer cells. Therefore, the present invention can be usefully used as a preventive or therapeutic agent for cancer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019103578-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200026106-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220131083-A |
| priorityDate |
2012-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |