| abstract |
The present invention relates to a method of treating, preventing or managing cancer, including certain leukemias. This method can be used to prepare enantiomerically pure (+) - 1,4-dihydro-7 - [(3S, 4S) -3- methoxy- 4- (methylamino) -1- pyrrolidinyl] - (2-thiazolyl) -l, 8-naphthyridine-3-carboxylic acid. The present invention also relates to methods of treatment using such compounds in conjunction with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. And to pharmaceutical compositions and single unit dosage forms suitable for use in such methods. |