| abstract |
The present invention provides a polypeptide comprising a complement factor B analog. The present invention also provides various complement factor B analogs and related methods, nucleic acids and vectors containing complement factor B analogs comprising mutations of free cysteine amino acids. These complement factor B analogs and related methods, nucleic acids and vectors can be used to modulate the complement pathway or for the study and / or treatment of various diseases or disorders related to the complement pathway. |